Bone formation ability of carbonate apatite-collagen scaffolds with different carbonate contents

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In vitro and in vivo evaluation of carbonate apatite-collagen scaffolds with some cytokines for bone tissue engineering

BACKGROUND Collagen is regarded as one of the most useful biomaterials. We tried to combine collagen and carbonate apatite (CA) with some cytokines in order to enhance bone formation ability. In this study, we found that CA-collagen sponge (CA-CS) was a possible candidate of newly graft material for bone formation. MATERIALS AND METHODS CA-CS was fabricated by the following procedure. One wt%...

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Formation and in Vivo Evaluation of Carbonate Apatite and Carbonate Apatite/CaCO_{3} Composite Films Using the Thermal Substrate Method in Aqueous Solution

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Properties of calcium carbonate-containing composite scaffolds.

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Carbonate apatite (CO₃Ap) foam has gained much attention in recent years because of its ability to rapidly replace bone. However, its mechanical strength is extremely low for clinical use. In this study, to understand the potential of gelatin-reinforced CO₃Ap foam for bone replacement, CO₃Ap foam was reinforced with gelatin and the resulting physical characteristics were evaluated. The mechanic...

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ژورنال

عنوان ژورنال: Dental Materials Journal

سال: 2009

ISSN: 1881-1361,0287-4547

DOI: 10.4012/dmj.28.234